Malegra 50 (Sildenafil 50 mg)

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Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Malegra 50mg Tablet is to be taken with food.

Malegra consists of sildenafil citrate in its formula. Sildenafil citrate is an inhibitor of an enzyme known as Phosphodiesterase type 5 which is present in different parts of the body including male genital areas like the penis and the prostate gland.

Phosphodiesterase type 5 enzyme is responsible for the breakdown of cyclic Guanosine Monophosphate (cGMP), a substance that is required in the corpus cavernosum of the penis to produce an erection. Because PDE5 depletes the amount of cGMP from the penile tissue, it causes sexual dysfunction in males. Sildenafil citrate, when administered inside the body, works against this enzyme to prevent it from degrading cGMP and causes it to accumulate in the penis.

Hence, when a person is sexually stimulated, nitric oxide is produced which reacts with cGMP to cause a relaxing effect on the muscles of the corpus cavernosum. Also, it causes a dilating effect on the vessels supplying the penis and helps in opening up the blocked arteries around the genital area. This permits more blood to flow towards the penis and also smoothens the penile muscles causing an erection to occur easily. In addition to this, the drug also exerts its effects in order to recover more quickly after experiencing an ejaculation. The drug works best when a person is already stimulated sexually.

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Nausea or vomiting
Conventional medicine that is composed of Sildenafil Citrate may make you feel dizzy or cause vision problems. Hence, avoid performing activities including driving, using machinery, or performing any activity which requires alertness or clear vision until you are sure you can perform such activities safely.

Men with last 6 months of conditions myocardial infarction, stroke, or life-threatening arrhythmic men should not consume this ED medicine.

Condition like loss of vision in one or both eyes may be a sign of non-arteritic anterior ischemic optic neuropathy (NAION) that may happen while consumption of PDE5 inhibitor like Sildenafil Citrate.

Limit intake of alcoholic beverages while consuming Malegra 50.

Excessive intake of medicine may lead to prolonged erection that is not safe. Limit intake of medicine as consume it as prescribed by doctor.

Patients consuming conventional tablet composed of Sildenafil Citrate with cardiac failure or coronary artery disease may cause unstable angina.


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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